Author  
Place of duty  
Title   융모성 종양의 치료에 있어서 수술요법의 의의 ( Clinical Analysis of the Efficacy of Surgical Treatment of Gastational Trophobastic Disease )
Publicationinfo   1993 Jan; 025(05): 680-687.
Key_word   Gestational trophoblastic disease, Surgical efficacy
Full-Text  
Abstract   Between January 1973 and June 1992, 1852 patients were registered in the Department of Obstetrics and Gynecology, Catholic University Medical College, and 701 patients of them were recieved chemotherapy for gestational trophoblastic tumors. Among these patients, hyste- rectomy(n=160), pulmonary resection(n=18), craniotomy(n=7) and others(n=7) were performed. We analyzed these cases retrospectively and the results were as follows: 1) Initial hysterectomy for low risk GTT significantly reduced the number of courses of chemotherapy and duration of hospitalization comparing to either chemotherapy alone or chemotherapy with delayed hysterectomy. 2) If resistance develops to systemic chemotherapy, adjuvant hysterectomy should be considered in stage I or II. 3) Although surgical role in high risk patient is considered, the effectiveness of the surgery was lower than low risk patients. 4) Thoracotomy may be attempted to excise the resistant focus and reduced the number of courses of chemotherapy and duration of hospitalization. 5) Craniotomy may be required to provide acute symptom relief and should be combined systemic chemotherapy and intrsthecal MTX infusion. 6) The remarkable sensitivity of GTT to chemical treatment has not eliminated the need for surgery.
저 자   김미란(Mee Ran Kim),정재근(Jae Keun Jung),권용일(Yong Il Kwon),이경훈(Kyung Hoon Lee),김찬주(Chan Joo Kim),김승조(Seung Jo Kim)